ERK2 Rabbit Monoclonal Antibody
Product Specifications
Background
Act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of ERK2 requires its phosphorylation by upstream kinases. ERK2 is located in the cytoplasm of resting cells and translocates into the nucleus upon extracellular stimuli by active transport of a dimer. ERK2 is essential for placental development and ERK2 in the trophoblast compartment may be indispensable for the vascularization of the labyrinth.
Product Name Alternative
ERK; p38; p40; p41; ERT1; MAPK2; PRKM1; P42MAPK; p41mapk; MAPK
Gene Name
ERK2
Gene ID
5594
Swiss Prot
P28482
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC, IP
Field of Research
Apoptosis, TGF-beta signaling pathway, PI3K-Akt signaling pathway, MAPK signaling pathway, Jak-STAT signaling pathway
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, IHC 1:50-1:100, ICC 1:50-1:200, IP 1:10-1:20
Form
Liquid
Buffer
Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.
Modification
Unmodified
Molecular Weight
Calculated MW: 41 kDa; Observed MW: 41 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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