Phospho-TAOK1/2/3 (Ser181/Ser181/Ser177) Rabbit Monoclonal Antibody
Product Specifications
Background
Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. Phosphorylates MAP2K3, MAP2K6 and MARK2. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. Involved in G-protein coupled receptor signaling to p38/MAPK14. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of MAP2K3 and MAP2K6.
Product Name Alternative
DPK; JIK; hKFC-A; MAP3K18
Gene Name
Phospho-TAOK1/2/3 (Ser181/Ser181/Ser177)
Gene ID
51347/57551/9344
Swiss Prot
Q7L7X3/Q9H2K8/Q9UL54
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, IHC 1:50-1:100
Form
Liquid
Buffer
Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.
Modification
Phosphorylated
Molecular Weight
Calculated MW: 116 kDa; Observed MW: 105,116,138 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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