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CCDC98 Rabbit Monoclonal Antibody

Product Specifications

Background

Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs.

Product Name Alternative

ABRA1; ABRAXAS; FAM175A; ; ABRAXAS1

Gene Name

CCDC98

Swiss Prot

Q6UWZ7

Host

Rabbit

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, ICC, FC, IP

Purification

Affinity Purification

Dilution

WB 1:1000-1:2000, ICC 1:50-1:200, FC 1:20-1:100, IP 1:20-1:50

Form

Liquid

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Modification

Unmodified

Molecular Weight

Calculated MW: 47 kDa ; Observed MW: 50 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

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