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MLKL Rabbit Monoclonal Antibody

Product Specifications

Background

Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process.Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage.

Product Name Alternative

HMLKL; Mixed lineage kinase domain like; Mlkl; ; MLKL

Gene Name

MLKL

Swiss Prot

Q8NB16

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IP

Purification

Affinity Purification

Dilution

WB 1:1000-1:2000, IP 1:20-1:50

Form

Liquid

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Modification

Unmodified

Molecular Weight

54 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

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