PAG Rabbit Monoclonal Antibody
Product Specifications
Background
Negatively regulates TCR (T-cell antigen receptor) -mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor) -mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.
Product Name Alternative
CBP; Csk binding protein; PAG; PAG1; ; PAG1
Gene Name
PAG
Swiss Prot
Q9NWQ8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, FC, IP
Purification
Affinity Purification
Dilution
WB 1:1000-1:2000, IHC 1:100-1:200, FC 1:20-1:100, IP 1:20-1:50
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.
Modification
Unmodified
Molecular Weight
Calculated MW: 47 kDa ; Observed MW: 80 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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