PHF8 Rabbit Monoclonal Antibody
Product Specifications
Background
Histone lysine demethylase with selectivity for the di- and monomethyl states that plays a key role cell cycle progression, rDNA transcription and brain development. Demethylates mono- and dimethylated histone H3 'Lys-9' residue (H3K9Me1 and H3K9Me2), dimethylated H3 'Lys-27' (H3K27Me2) and monomethylated histone H4 'Lys-20' residue (H4K20Me1) . Acts as a transcription activator as H3K9Me1, H3K9Me2, H3K27Me2 and H4K20Me1 are epigenetic repressive marks. Involved in cell cycle progression by being required to control G1-S transition.
Product Name Alternative
Histone lysine demethylase PHF8; MRXSSD; PHD finger protein 8; PHF8; ZNF422; ; PHF8
Gene Name
PHF8
Swiss Prot
Q9UPP1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, ICC, IP
Purification
Affinity Purification
Dilution
WB 1:1000-1:2000, ICC 1:50-1:200, IP 1:20-1:50
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.
Modification
Unmodified
Molecular Weight
Calculated MW: 118 kDa ; Observed MW: 140 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K3218206 1.0 µg DNA
Gucy1a2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)
Sign In for Pricing
View Details 
FAB9919T-100UG 100 µg
Human APP (Solanezumab) Alexa Fluor 594 MAb (Clone Hu13)
Sign In for Pricing
View Details orb2902513-01 20 µg
Recombinant Mouse Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (St6galnac2)
Sign In for Pricing
View Details