Angiopoietin 2 Rabbit Monoclonal Antibody
Product Specifications
Background
Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
Product Name Alternative
AGPT 2; Agpt2; ANG2; Angiopoietin 2a; Angiopoietin 2B; Angiopoietin2; ANGPT 2; Angpt2; Tie2 ligand; ; Angiopoietin 2
Gene Name
Angiopoietin 2
Swiss Prot
O15123
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC
Purification
Affinity Purification
Dilution
WB 1:1000-1:2000, IHC 1:100-1:200
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.
Modification
Unmodified
Molecular Weight
Calculated MW: 57 kDa ; Observed MW: 50 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC682877-500 1x 500 µL
CD45RB (B-Cell Marker) (PTPRC/2877R), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC682590-100 1x 100 µL
CD10 (Membrane Metalloendopeptidase) (MME/2590), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC740633-100 1x 100 µL
Von Willebrand Factor (3E2D10), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 