Caspase 10 Rabbit Monoclonal Antibody
Product Specifications
Background
Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates effector caspases CASP3, CASP4, CASP6, CASP7, CASP8 and CASP9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC.
Product Name Alternative
Apoptotic protease Mch4; CASP10; Caspase10; FLICE2; ICE like apoptotic protease 4; FADD-like ICE2; ; Caspase 10
Gene Name
Caspase 10
Swiss Prot
Q92851
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, FC, IP
Purification
Affinity Purification
Dilution
WB 1:1000-1:2000, IHC 1:100-1:200, FC 1:20-1:100, IP 1:20-1:50
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.
Modification
Unmodified
Molecular Weight
59 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
034645-ML405 100 µL
DIO3, CT (DIO3, ITDI3, TXDI3, Type III iodothyronine deiodinase, 5DIII, DIOIII, Type 3 DI, Type-III 5'-deiodinase) (MaxLight 405) discontinued
Ask
View Details 
