STAT1 Rabbit Monoclonal Antibody
Product Specifications
Background
Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus.
Product Name Alternative
Signal transducer and activator of transcription 1; Signal transducer and activator of transcription 1-alpha/beta; Transcription factor ISGF-3 components p91/p84; ISGF3; CANDF7; STAT 1; Stat1; ; STAT1
Gene Name
STAT1
Swiss Prot
P42224
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, FC, IP
Purification
Affinity Purification
Dilution
WB 1:1000-1:2000, FC 1:20-1:100, IP 1:20-1:50
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.
Modification
Unmodified
Molecular Weight
Calculated MW: 87 kDa ; Observed MW: 84 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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