Tuberin Rabbit Monoclonal Antibody
Product Specifications
Background
Catalytic component of the TSC-TBC complex, a multiprotein complex that acts as a negative regulator of the canonical mTORC1 complex, an evolutionarily conserved central nutrient sensor that stimulates anabolic reactions and macromolecule biosynthesis to promote cellular biomass generation and growth.Within the TSC-TBC complex, TSC2 acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1.
Product Name Alternative
TSC2; Tuberous sclerosis 2 homolog protein; Tuberous sclerosis 2 protein; Tuberin; ; Tuberin
Gene Name
Tuberin
Swiss Prot
P49815
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, FC
Purification
Affinity Purification
Dilution
WB 1:1000-1:2000, IHC 1:100-1:200, FC 1:20-1:100
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.
Modification
Unmodified
Molecular Weight
Calculated MW: 201 kDa ; Observed MW: 200 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC883007-100 1x 100 µL
VISTA / B7-H5 / VSIR (Negative Regulator of Immune Response) (VISTA/3007), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
KN401218 1 Kit
Cardiac Troponin T (TNNT2) Human Gene Knockout Kit (CRISPR)
Sign In for Pricing
View Details 
BNC402079-100 1x 100 µL
TCL1 (T-Cell Marker) (TCL1/2079), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNUB2498-100 1x 100 µL
Bcl-6 (Follicular Lymphoma Marker) (rBCL6/1718), 0.2mg/mL
Sign In for Pricing
View Details 