Tuberin Rabbit Monoclonal Antibody
Product Specifications
Background
Catalytic component of the TSC-TBC complex, a multiprotein complex that acts as a negative regulator of the canonical mTORC1 complex, an evolutionarily conserved central nutrient sensor that stimulates anabolic reactions and macromolecule biosynthesis to promote cellular biomass generation and growth.Within the TSC-TBC complex, TSC2 acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1.
Product Name Alternative
TSC2; Tuberous sclerosis 2 homolog protein; Tuberous sclerosis 2 protein; Tuberin; ; Tuberin
Gene Name
Tuberin
Swiss Prot
P49815
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, FC
Purification
Affinity Purification
Dilution
WB 1:1000-1:2000, IHC 1:100-1:200, FC 1:20-1:100
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.
Modification
Unmodified
Molecular Weight
Calculated MW: 201 kDa ; Observed MW: 200 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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