Cdc23/APC8 Rabbit Monoclonal Antibody
Product Specifications
Background
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Product Name Alternative
CDC23; ANAPC8; APC8; Cell division cycle 23; CUT23; Cyclosome subunit 8; ; CDC23
Gene Name
Cdc23/APC8
Swiss Prot
Q9UJX2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, ICC
Purification
Affinity Purification
Dilution
WB 1:1000-1:2000, ICC 1:50-1:200
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.
Modification
Unmodified
Molecular Weight
Calculated MW: 69 kDa ; Observed MW: 64 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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