Caspase-1 Rabbit Monoclonal Antibody

Product Specifications

Background

Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs) . Can also promote apoptosis.

Product Name Alternative

CASP-1; ICE; IL-1 beta converting enzyme; IL-1BC; IL1BCE; caspase-1; ; Caspase 1

Gene Name

Caspase-1

Swiss Prot

P29466

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IP

Purification

Affinity Purification

Dilution

WB 1:1000-1:2000, IP 1:20-1:50

Form

Liquid

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Modification

Unmodified

Molecular Weight

Calculated MW: 45 kDa ; Observed MW: 45,42,35,12,10 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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