HN1 Rabbit Monoclonal Antibody
Product Specifications
Background
Modulates negatively AKT-mediated GSK3B signaling.Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions.
Product Name Alternative
ARM2; HN1; HN1A; ; JPT1
Gene Name
HN1
Swiss Prot
Q9UK76
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, ICC, FC
Purification
Affinity Purification
Dilution
WB 1:1000-1:2000, ICC 1:50-1:200, FC 1:20-1:100
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.
Modification
Unmodified
Molecular Weight
Calculated MW: 16 kDa ; Observed MW: 21 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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