TMEM173 Rabbit Monoclonal Antibody
Product Specifications
Background
Cell localization:Cytoplasmic, Membranous.This gene encodes a five transmembrane protein that functions as a major regμLator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vascμLopathy. Alternate splicing resμLts in mμLtiple transcript variants. [provided by RefSeq, Sep 2014]
Product Name Alternative
TMEM173; ERIS; MITA; STING; Transmembrane protein 173; Endoplasmic reticμLum interferon stimμLator; ERIS; Mediator of IRF3 activation; hMITA; StimμLator of interferon genes protein; hSTING
Gene Name
TMEM173 ERIS MITA STING
Gene ID
340061
Swiss Prot
Q86WV6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA, IP
Purification
Protein A
Dilution
WB 1:1000-1:5000, IHC 1:200-1:1000, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200
Form
Liquid
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Modification
Unmodified
Molecular Weight
CalcμLated MW:42kD; Observed MW:37kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG, Kappa
Available Sizes
Curated Selection
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