EEA1 Rabbit Monoclonal Antibody
Product Specifications
Background
Cell localization:Cytoplasm.disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases., domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate., function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking., similarity:Contains 1 C2H2-type zinc finger., similarity:Contains 1 FYVE-type zinc finger., subunit:Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding.
Product Name Alternative
EEA1; ZFYVE2; Early endosome antigen 1; Endosome-associated protein p162; Zinc finger FYVE domain-containing protein 2
Gene Name
EEA1
Gene ID
8411
Swiss Prot
Q15075
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA, IP
Purification
Protein A
Dilution
WB 1:1000-1:5000, IHC 1:100-1:200, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200
Form
Liquid
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Modification
Unmodified
Molecular Weight
CalcμLated MW:162kD; Observed MW:162kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG, Kappa
Available Sizes
Curated Selection
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