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NADPH oxidase 4 Rabbit Monoclonal Antibody

Product Specifications

Background

Cell localization:Cytoplasm.This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecμLar oxygen to various reactive oxygen species (ROS) . The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing resμLts in mμLtiple transcript variants.[provided by RefSeq, Jan 2009]

Gene Name

NOX4 RENOX

Gene ID

50507

Swiss Prot

Q9NPH5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, ICC/IF, ELISA, IP

Purification

Protein A

Dilution

WB 1:1000-1:5000, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200

Form

Liquid

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Modification

Unmodified

Molecular Weight

CalcμLated MW:67kD; Observed MW:67kD

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG, Kappa

Available Sizes

Curated Selection

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