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COX2 Rabbit Monoclonal Antibody

Product Specifications

Background

Cell localization:Cytoplasm.Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regμLation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regμLated by specific stimμLatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]

Gene Name

PTGS2 COX2

Gene ID

5743

Swiss Prot

P35354

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, ELISA

Purification

Protein A

Dilution

WB 1:1000-1:5000, IHC 1:100-1:500, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000

Form

Liquid

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Modification

Unmodified

Molecular Weight

CalcμLated MW:69kD; Observed MW:75kD

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG, Kappa

Available Sizes

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