COX2 Rabbit Monoclonal Antibody
Product Specifications
Background
Cell localization:Cytoplasm.Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regμLation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regμLated by specific stimμLatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
Gene Name
PTGS2 COX2
Gene ID
5743
Swiss Prot
P35354
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Purification
Protein A
Dilution
WB 1:1000-1:5000, IHC 1:100-1:500, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000
Form
Liquid
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Modification
Unmodified
Molecular Weight
CalcμLated MW:69kD; Observed MW:75kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG, Kappa
Available Sizes
Curated Selection
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