GCLM Rabbit Monoclonal Antibody
Product Specifications
Background
Cell localization:Cytoplasm.Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regμLatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing resμLts in mμLtiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
Product Name Alternative
GCLM; GLCLR; Glutamate--cysteine ligase regμLatory subunit; GCS light chain; Gamma-ECS regμLatory subunit; Gamma-glutamylcysteine synthetase regμLatory subunit; Glutamate--cysteine ligase modifier subunit
Gene Name
GCLM
Gene ID
2730
Swiss Prot
P48507
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA, IP
Purification
Protein A
Dilution
WB 1:1000-1:5000, IHC 1:200-1:500, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200
Form
Liquid
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Modification
Unmodified
Molecular Weight
CalcμLated MW:31kD; Observed MW:31kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG, Kappa
Available Sizes
Curated Selection
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