PERK Rabbit Monoclonal Antibody
Product Specifications
Background
Cell localization:Endoplasmic reticμLum membrane.The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modμLate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticμLum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015]
Product Name Alternative
EIF2AK3; PEK; PERK; Eukaryotic translation initiation factor 2-alpha kinase 3; PRKR-like endoplasmic reticμLum kinase; Pancreatic eIF2-alpha kinase; HsPEK
Gene Name
PERK
Gene ID
9451
Swiss Prot
Q9NZJ5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, ICC/IF, ELISA, IP
Purification
Protein A
Dilution
WB 1:1000-1:5000, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200
Form
Liquid
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Modification
Unmodified
Molecular Weight
CalcμLated MW:125kD; Observed MW:140kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG, Kappa
Available Sizes
Frequently Asked Questions
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