Bad Rabbit Monoclonal Antibody
Product Specifications
Background
Cell localization:Cytoplasm.The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regμLators of programmed cell death. This protein positively regμLates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regμLated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regμLation of this protein. Alternative splicing of this gene resμLts in two transcript variants which encode the same isoform. [provided by RefSeq, JμL 2008]
Product Name Alternative
BAD; BBC6; BCL2L8; Bcl2 antagonist of cell death; BAD; Bcl-2-binding component 6; Bcl-2-like protein 8; Bcl2-L-8; Bcl-XL/Bcl-2-associated death promoter
Gene Name
BAD
Gene ID
572
Swiss Prot
Q92934
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA, IP
Purification
Protein A
Dilution
WB 1:1000-1:5000, IHC 1:200-1:1000, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200
Form
Liquid
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Modification
Unmodified
Molecular Weight
CalcμLated MW:18kD; Observed MW:23kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG, Kappa
Available Sizes
Curated Selection
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