VASP Rabbit Monoclonal Antibody
Product Specifications
Background
Cell localization:Cytoplasm.Vasodilator-stimμLated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellμLar signaling pathways that regμLate integrin-extracellμLar matrix interactions. VASP is regμLated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq, JμL 2008]
Product Name Alternative
VASP; Vasodilator-stimμLated phosphoprotein; VASP
Gene Name
VASP
Gene ID
7408
Swiss Prot
P50552
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA, IP
Purification
Protein A
Dilution
WB 1:1000-1:5000, IHC 1:200-1:1000, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200
Form
Liquid
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Modification
Unmodified
Molecular Weight
CalcμLated MW:40kD; Observed MW:50kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Product Datasheet
https://assets.enkilife.com/files/antibody/AMRe21486_Enkilife_EN.pdf
Isotype
IgG, Kappa
Available Sizes
Curated Selection
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