SIRT3 Rabbit Monoclonal Antibody
Product Specifications
Background
Cell localization:Mitochondrion matrix.This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regμLate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellμLar regμLatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, JμL 2008]
Product Name Alternative
SIRT3; SIR2L3; NAD-dependent protein deacetylase sirtuin-3; mitochondrial; hSIRT3; RegμLatory protein SIR2 homolog 3; SIR2-like protein 3
Gene Name
SIRT3
Gene ID
23410
Swiss Prot
Q9NTG7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA, IP
Purification
Protein A
Dilution
WB 1:1000-1:5000, IHC 1:200-1:1000, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200
Form
Liquid
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Modification
Unmodified
Molecular Weight
CalcμLated MW:44kD; Observed MW:28kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG, Kappa
Available Sizes
Frequently Asked Questions
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