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FTO Rabbit Monoclonal Antibody

Product Specifications

Background

Cell localization:Cytoplasm, Nucleus.This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascμLar systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, JμL 2011]

Product Name Alternative

FTO; KIAA1752; Alpha-ketoglutarate-dependent dioxygenase FTO; Fat mass and obesity-associated protein

Gene Name

FTO

Gene ID

79068

Swiss Prot

Q9C0B1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, ELISA, IP

Purification

Protein A

Dilution

WB 1:1000-1:5000, IHC 1:3000-1:20000, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200

Form

Liquid

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Modification

Unmodified

Molecular Weight

CalcμLated MW:58kD; Observed MW:58kD

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG, Kappa

Available Sizes

Frequently Asked Questions

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