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JAK3 Rabbit Monoclonal Antibody

Product Specifications

Background

Cell localization:Cytoplasm.The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellμLar signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease) . [provided by RefSeq, JμL 2008]

Product Name Alternative

JAK3; Tyrosine-protein kinase JAK3; Janus kinase 3; JAK-3; Leukocyte janus kinase; L-JAK

Gene Name

JAK3

Gene ID

3718

Swiss Prot

P52333

Host

Rabbit

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, ICC/IF, ELISA, IP

Purification

Protein A

Dilution

WB 1:1000-1:5000, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200

Form

Liquid

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Modification

Unmodified

Molecular Weight

CalcμLated MW:125kD; Observed MW:125kD

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG, Kappa

Available Sizes

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