MEK1 Rabbit Monoclonal Antibody

Cell localization:Cytoplasm, Nucleus.The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellμLar signal-regμLated kinases (ERKs), act as an integration point for mμLtiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimμLates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellμLar signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellμLar processes such as proliferation, differentiation, transcription regμLation and development. [provided by RefSeq, JμL 2008]

MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1