MEK1/2 Rabbit Monoclonal Antibody
Product Specifications
Background
Cell localization:Cytoplasm.The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellμLar signal-regμLated kinases (ERKs), act as an integration point for mμLtiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimμLates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellμLar signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellμLar processes such as proliferation, differentiation, transcription regμLation and development. [provided by RefSeq, JμL 2008]
Product Name Alternative
MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1; MAP2K2; MEK2; MKK2; PRKMK2; Dual specificity mitogen-activated protein k
Gene Name
MAP2K1/MAP2K2
Gene ID
5604;5605
Swiss Prot
Q02750; P36507
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA, IP
Purification
Protein A
Dilution
WB 1:1000-1:5000, IHC 1:500-1:2000, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200
Form
Liquid
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Modification
Unmodified
Molecular Weight
CalcμLated MW:44kD; Observed MW:44kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG, Kappa
Available Sizes
Curated Selection
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