Caldesmon Rabbit Monoclonal Antibody
Product Specifications
Background
Cell localization:Cytoplasm.This gene encodes a calmodμLin- and actin-binding protein that plays an essential role inThe regμLation of smooth muscle and nonmuscle contraction.The conserved domain of this protein possessesThe binding activities to Ca (2+) -calmodμLin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor ofThe actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca (2+) -dependent inhibition of smooth muscle contraction. Alternative splicing of this gene resμLts in mμLtiple transcript variants encoding distinct isoforms. [provided by RefSeq, JμL 2008]
Product Name Alternative
CALD1; CAD; CDM; Caldesmon; CDM
Gene Name
CALD1
Gene ID
800
Swiss Prot
Q05682
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA, IP
Purification
Protein A
Dilution
WB 1:2000-1:10000, IHC 1:200-1:1000, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200
Form
Liquid
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Modification
Unmodified
Molecular Weight
CalcμLated MW:93kD; Observed MW:70kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG, Kappa
Available Sizes
Frequently Asked Questions
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