C-Jun Rabbit Monoclonal Antibody
Product Specifications
Background
Cell localization:Nucleus.function:Transcription factor that recognizes and binds toThe enhancer heptamer motif 5'-TGA[CG]TCA-3'., PTM:Phosphorylation enhancesThe transcriptional activity. Phosphorylated by PRKDC., similarity:Belongs toThe bZIP family., similarity:Belongs toThe bZIP family. Jun subfamily., similarity:Contains 1 bZIP domain., subunit:Heterodimer with either FOS or BATF3. Interacts with HIVEP3 (By similarity) . Interacts with SMAD3/SMAD4 heterodimers. Interacts with MYBBP1A, SPIB and TCF20. Interacts with COPS5; indirectly leading to its phosphorylation. Interacts with DSIPI; this interaction inhibitsThe binding of active AP1 to its target DNA.
Product Name Alternative
Transcription factor AP-1 (Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39)
Gene Name
JUN
Gene ID
3725
Swiss Prot
P05412
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA, IP
Purification
Protein A
Dilution
WB 1:2000-1:10000, IHC 1:200-1:1000, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200
Form
Liquid
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Modification
Unmodified
Molecular Weight
CalcμLated MW:36kD; Observed MW:43kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG, Kappa
Available Sizes
Curated Selection
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