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Keap1 Rabbit Monoclonal Antibody

Product Specifications

Background

Cell localization:Cytoplasm, Nucleus.kelch like ECH associated protein 1 (KEAP1) Homo sapiens This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction resμLts in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, JμL 2008]

Product Name Alternative

Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (INrf2) (Kelch-like protein 19)

Gene Name

KEAP1 INRF2 KIAA0132 KLHL19

Gene ID

9817

Swiss Prot

Q14145

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, ELISA, IP

Purification

Protein A

Dilution

WB 1:2000-1:10000, IHC 1:200-1:1000, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200

Form

Liquid

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Modification

Unmodified

Molecular Weight

CalcμLated MW:70kD; Observed MW:60-70kD

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Product Datasheet

https://assets.enkilife.com/files/antibody/AMRe21357_Enkilife_EN.pdf

Isotype

IgG, Kappa

Available Sizes

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