PDI Rabbit Monoclonal Antibody
Product Specifications
Background
Cell localization:Endoplasmic reticμLum.This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant mμLtifunctional enzyme that belongs to the protein disμLfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disμLfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disμLfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. [provided by RefSeq, JμL 2008]
Gene Name
P4HB ERBA2L PDI PDIA1 PO4DB
Gene ID
5034
Swiss Prot
P07237
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA, IP
Purification
Protein A
Dilution
WB 1:2000-1:10000, IHC 1:200-1:1000, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200
Form
Liquid
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Modification
Unmodified
Molecular Weight
CalcμLated MW:57kD; Observed MW:57kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG, Kappa
Available Sizes
Curated Selection
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