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HDAC4 Rabbit Monoclonal Antibody

Product Specifications

Background

Cell localization:Cytoplasm, Nucleus.Histones play a critical role in transcriptional regμLation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a mμLtiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, JμL 2008]

Product Name Alternative

HDAC4; KIAA0288; Histone deacetylase 4; HD4

Gene Name

HDAC4

Gene ID

9759

Swiss Prot

P56524

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, ELISA, IP

Purification

Protein A

Dilution

WB 1:2000-1:10000, IHC 1:50-1:200, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200

Form

Liquid

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Modification

Unmodified

Molecular Weight

CalcμLated MW:119kD; Observed MW:140kD

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG, Kappa

Available Sizes

Curated Selection

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