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GAPDH Rabbit Monoclonal Antibody

Product Specifications

Background

Cell localization:Cytoplasm, Nucleus.glyceraldehyde-3-phosphate dehydrogenase (GAPDH) Homo sapiens This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD) . The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regμLation of mRNA stability, and acting as a transferri

Product Name Alternative

GAPDH; GAPD; CDABP0047; OK/SW-cl.12; Glyceraldehyde-3-phosphate dehydrogenase; GAPDH; Peptidyl-cysteine S-nitrosylase GAPDH

Gene Name

GAPDH

Gene ID

2597

Swiss Prot

P04406

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, ELISA, IP

Purification

Protein A

Dilution

WB 1:10000-1:50000, IHC 1:2000-1:5000, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200

Form

Liquid

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Modification

Unmodified

Molecular Weight

CalcμLated MW:38kD; Observed MW:38kD

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG, Kappa

Available Sizes

Curated Selection

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