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PAX6 Rabbit Monoclonal Antibody

Product Specifications

Background

Cell localization:Nucleus.This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regμLator of transcription. Activity of this protein is key in the development of neural tissues, particμLarly the eye. This gene is regμLated by mμLtiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocμLar disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing resμLt in mμLtiple transcript variants encoding different isoforms. [provided by RefSeq, JμL 2015]

Product Name Alternative

Paired box protein Pax-6; Aniridia type II protein; OcμLorhombin

Gene Name

PAX6 AN2

Gene ID

5080

Swiss Prot

P26367

Host

Rabbit

Reactivity

Human, Mouse

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, ELISA, IP

Purification

Protein A

Dilution

WB 1:2000-1:10000, IHC 1:200-1:1000, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200

Form

Liquid

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Modification

Unmodified

Molecular Weight

CalcμLated MW:47kD; Observed MW:47kD

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG, Kappa

Available Sizes

Curated Selection

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