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STARD4 Rabbit Monoclonal Antibody

Product Specifications

Background

Cholesterol homeostasis is regμLated, at least in part, by sterol regμLatory element (SRE) -binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423) . Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regμLatory protein (STAR; MIM 600617) . STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]) .[supplied by OMIM, Mar 2008]

Product Name Alternative

STARD4; StAR-related lipid transfer protein 4 ; START domain-containing protein 4; StARD4

Gene Name

STARD4

Gene ID

134429

Swiss Prot

Q96DR4

Host

Rabbit

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, ICC/IF

Purification

Protein A

Dilution

WB 1:1000-1:5000, ICC/IF 1:100-1:300

Form

Liquid

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Modification

Unmodified

Molecular Weight

CalcμLated MW:; Observed MW:23kD

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG, Kappa

Available Sizes

Curated Selection

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