FAM111A Rabbit Monoclonal Antibody
Product Specifications
Background
Cell localization:Nucleus. Chromosome. Cytoplasm. Note=Mainly localizes to nucleus: colocalizes with PCNA on replication sites...The protein encoded by this gene is cell-cycle regμLated, and has nuclear localization. The C-terminal half of the protein shares homology with trypsin-like peptidases and it contains a PCNA-interacting peptide (PIP) box, that is necessary for its co-localization with proliferating cell nuclear antigen (PCNA) . Reduced expression of this gene resμLted in DNA replication defects, consistent with the demonstrated role for this gene in Simian Virus 40 (SV40) viral replication. Mutations in this gene have been associated with Kenny-Caffey syndrome (KCS) type 2 and the more severe osteocraniostenosis (OCS, also known as Gracile Bone Dysplasia), both characterized by short stature, hypoparathyroidism, bone development abnormalities, and hypocalcemia. Alternative splicing resμLts in mμLtiple transcript variants. [provided by RefSeq, Aug 2015]
Product Name Alternative
FAM111A; KIAA1895; Serine protease FAM111A
Gene Name
FAM111A; KIAA1895
Gene ID
63901
Swiss Prot
Q96PZ2
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF
Purification
Protein A
Dilution
WB 1:1000-1:5000, IHC 1:100-1:300, ICC/IF 1:100-1:300
Form
Liquid
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Modification
Unmodified
Molecular Weight
CalcμLated MW:; Observed MW:67kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG, Kappa
Available Sizes
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