BRAT1 Rabbit Monoclonal Antibody
Product Specifications
Background
Cell localization:Nucleus. Cytoplasm. Note=Present at double strand breaks (DSBs) following ionizing radiation treatment. The ubiquitinated form localizes in the nucleus in a NDFIP1-dependent manner...The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellμLar responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the mμLti-protein complex BASC (BRAC1-associated genome surveillance complex) . The protein encoded by this gene is thought to play a role in the DNA damage pathway regμLated by BRCA1 and ATM. [provided by RefSeq, Mar 2012]
Product Name Alternative
BRAT1; BAAT1; C7orf27; BRCA1-associated ATM activator 1 ; BRCA1-associated protein required for ATM activation protein 1
Gene Name
BRAT1; BAAT1; C7orf27
Gene ID
221927
Swiss Prot
Q6PJG6
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, ICC/IF, FC, IP
Purification
Protein A
Dilution
WB 1:1000-1:5000, ICC/IF 1:100-1:300, FC 1:100-1:300, IP 1:50-1:100
Form
Liquid
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Modification
Unmodified
Molecular Weight
CalcμLated MW:; Observed MW:90kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG, Kappa
Available Sizes
Curated Selection
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