TAF1C Rabbit Monoclonal Antibody

Cell localization:Nucleus, nucleolus..Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regμLatory signals. This gene encodes the largest SL1-specific TAF. MμLtiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, JμL 2011]

TAF1C; TATA box-binding protein-associated factor RNA polymerase I subunit C ; RNA polymerase I-specific TBP-associated factor 110 kDa; TAFI110; TATA box-binding protein-associated factor 1C; TBP-associated factor 1C; Transcription initiation factor SL1/TIF-IB subunit C