JNK1/2/3 Rabbit Monoclonal Antibody
Product Specifications
Background
Cell localization:Nucleus.The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for mμLtiple biochemical signals, and are involved in a wide variety of cellμLar processes such as proliferation, differentiation, transcription regμLation and development. This kinase is activated by various cell stimμLi, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimμLi. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spl
Product Name Alternative
MAPK8; JNK1; PRKM8; SAPK1; SAPK1C; Mitogen-activated protein kinase 8; MAP kinase 8; MAPK 8; JNK-46; Stress-activated protein kinase 1c; SAPK1c; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1; MAPK9; JNK2; PRKM9; SAPK1A; Mi
Gene Name
MAPK8/9/10
Gene ID
5599;5601;5602
Swiss Prot
P45983; P45984; P53779
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, ICC/IF, ELISA, IP
Purification
Protein A
Dilution
WB 1:2000-1:10000, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200
Form
Liquid
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Modification
Unmodified
Molecular Weight
CalcμLated MW:48,53kD; Observed MW:48,53kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG, Kappa
Available Sizes
Curated Selection
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