Met Rabbit Monoclonal Antibody
Product Specifications
Background
Cell localization:Secreted.This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disμLfide bonds to form the mature receptor. Further processing of the beta subunit resμLts in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellμLar survival, embryogenesis, and cellμLar migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellμLar carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with mμLtiple human cancers. [provided by RefSeq, May 2016]
Product Name Alternative
MET; Hepatocyte growth factor receptor; HGF receptor; HGF/SF receptor; Proto-oncogene c-Met; Scatter factor receptor; SF receptor; Tyrosine-protein kinase Met
Gene Name
MET
Gene ID
4233
Swiss Prot
P08581
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA, IP
Purification
Protein A
Dilution
WB 1:2000-1:10000, IHC 1:200-1:1000, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200
Form
Liquid
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Modification
Unmodified
Molecular Weight
CalcμLated MW:156kD; Observed MW:170kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Product Datasheet
https://assets.enkilife.com/files/antibody/AMRe21182_Enkilife_EN.pdf
Isotype
IgG, Kappa
Available Sizes
Curated Selection
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