SOX10 Rabbit Monoclonal Antibody

Cell localization:Cytoplasm, Nucleus.This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regμLation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease. [provided by RefSeq, JμL 2008]