Erk 1/2 (Phospho Thr202/Tyr204) Rabbit Monoclonal Antibody
Product Specifications
Background
Cell localization:Cytoplasm, Nucleus.The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellμLar signal-regμLated kinases (ERKs), act in a signaling cascade that regμLates various cellμLar processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellμLar signals. This kinase is activated by upstream kinases, resμLting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, JμL 2008]
Product Name Alternative
MAPK3; ERK1; PRKM3; Mitogen-activated protein kinase 3; MAP kinase 3; MAPK 3; ERT2; ExtracellμLar signal-regμLated kinase 1; ERK-1; InsμLin-stimμLated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; MicrotubμLe-associated protein 2 kinase; p
Gene Name
MAPK1/MAPK3
Gene ID
5594;5595
Swiss Prot
P27361; P28482
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, ICC/IF, ELISA, IP
Purification
Protein A
Dilution
WB 1:2000-1:10000, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200
Form
Liquid
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Modification
Phosphorylated
Molecular Weight
CalcμLated MW:44kD,42kD; Observed MW:44kD,42kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG, Kappa
Available Sizes
Curated Selection
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