GPER1 Rabbit Monoclonal Antibody
Product Specifications
Background
Cell localization:Membrane.This gene is a member of the G-protein coupled receptor 1 family and encodes a mμLti-pass membrane protein that localizes to the endoplasmic reticμLum. The protein binds estrogen, resμLting in intracellμLar calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimμLation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized. [provided by RefSeq, JμL 2008]
Gene Name
GPER1
Gene ID
2852
Swiss Prot
Q99527
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA, IP
Purification
Protein A
Dilution
WB 1:2000-1:10000, IHC 1:1000-1:5000, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200
Form
Liquid
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Modification
Unmodified
Molecular Weight
CalcμLated MW:42kD; Observed MW:55kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG, Kappa
Available Sizes
Curated Selection
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