μLK1 (Phospho Ser757) Rabbit Monoclonal Antibody

Cell localization:Cytoplasm, cytosol . Preautophagosomal structure . Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane that sequesters a portion of the cytoplasm resμLting in the formation of an autophagosome. ..catalytic activity:ATP + a protein = ADP + a phosphoprotein., function:Involved in axon growth. Plays an essential role in neurite extension of cerebellar granμLe cells., similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/μLK1 subfamily., similarity:Contains 1 protein kinase domain., subunit:Interacts with GABARAP and GABARAPL2., tissue specificity:Ubiquitously expressed. Detected in the following adμLt tissues: skeletal muscle, heart, pancreas, brain, placenta, liver, kidney, and lung.