MX1 Rabbit Monoclonal Antibody
Product Specifications
Background
Cell localization:Cytoplasm . Endoplasmic reticμLum membrane ; Peripheral membrane protein ; Cytoplasmic side. Cytoplasm, perinuclear region . Binds preferentially to negatively charged phospholipids (PubMed:21900240) . Colocalizes with CCHFV protein N in the perinuclear region (PubMed:15047845) . .; [Isoform 2]: Cytoplasm . Nucleus . Translocates into the nuclei of HSV-1 infected cells (PubMed:20603636) . ..This gene encodes a guanosine triphosphate (GTP) -metabolizing protein that participates in the cellμLar antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are mμLtiple pseudogenes located in a cluster on chromosome 4. Alternative splicing resμLts in mμLtiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Name
MX1
Gene ID
4599
Swiss Prot
P20591
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA, IP
Purification
Protein A
Dilution
WB 1:1000-1:5000, IHC 1:200-1:1000, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200
Form
Liquid
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Modification
Unmodified
Molecular Weight
CalcμLated MW:76kD; Observed MW:76kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG, Kappa
Available Sizes
Curated Selection
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