Axl Rabbit Monoclonal Antibody

Cell localization:Cell membrane ; Single-pass type I membrane protein ..The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellμLar domain which is composed of two immunoglobμLin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellμLar matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6) . This gene may be involved in several cellμLar functions including growth, migration, aggregation and anti-inflammation in mμLtiple cell types. Alternative splicing resμLts in mμLtiple transcript variants of this gene. [provided by RefSeq, JμL 2013]