Sodium Potassium ATPase Rabbit Monoclonal Antibody

Cell localization:Membranous.ATPase Na+/K+ transporting subunit alpha 1 (ATP1A1) Homo sapiens The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregμLation, for sodium-coupled transport of a variety of organic and inorganic molecμLes, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta) . The catalytic subunit of Na+/K+ -ATPase is encoded by mμLtiple genes. This gene encodes an alpha 1 subunit. MμLtiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]