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Phospho-p53 (S392) (9G13) Rabbit Monoclonal Antibody

Product Specifications

Background

Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.

Product Name Alternative

Antigen NY-CO-13, Cellular tumor antigen p53, Phosphoprotein p53, TP53, Tumor suppressor p53

Swiss Prot

P04637

Host

Rabbit

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC

Field of Research

Cell Biology

Purification

Affinity purification

Dilution

WB 1:1000-1:5000, IHC 1:100-1:200

Form

Liquid

Buffer

Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

Modification

Phosphorylated

Molecular Weight

44kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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