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Troponin T (15D11) Rabbit Monoclonal Antibody

Product Specifications

Background

Troponin, working in conjunction with tropomyosin, functions as a molecular switch, regulating muscle contraction in response to changes in the intracellular Ca2+ concentration. Troponin consists of three subunits: the Ca2+-binding subunit troponin C (TnC), the tropomyosin-binding subunit troponin T (TnT), and the inhibitory subunit troponin I (TnI) . Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

Product Name Alternative

TNNT2 ; Cardiac muscle troponin T; Troponin T, cardiac muscle; troponin T type 2 (cardiac)

Gene Name

TNNT2

Gene ID

7139

Swiss Prot

P45379

Host

Rabbit

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, IP, IF-P

Purification

Affinity purification

Dilution

WB 1:500-1:2000, IHC 1:200-1:500, IP 1:50-1:100, IF-P 1:200-1:500

Form

Liquid

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Modification

Unmodified

Molecular Weight

36kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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