Cytokeratin 20 (8W19) Rabbit Monoclonal Antibody

Product Specifications

Background

Intermediate-sized filament (IF) protein designated cytokeratin (CK) 20 is a major cellular protein of mature enterocytes and goblet cells commonly found in mucosal epithelium of the mammalian gastrointestinal tract. Results strongly suggest that transcriptional regulation of keratin genes in the intestinal epithelium occurs at the level of both immature and terminally differentiated epithelial cells, and is tightly regulated during both fetal development and crypt-to-villus differentiation of the intestinal epithelium. Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity) .

Product Name Alternative

CD20; CK-20; CK20; cytokeratin 20; Cytokeratin-20; K1C20; K20; keratin 20; Keratin, type I cytoskeletal 20; Keratin-20; KRT20; KRT21; MGC35423; Protein IT

Gene Name

KRT20

Gene ID

54474

Swiss Prot

P35900

Host

Rabbit

Reactivity

Human, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, FC

Purification

Affinity purification

Dilution

WB 1:2000-1:20000, IHC 1:100-1:200, ICC/IF 1:100-1:500, FC 1:200-1:1000

Form

Liquid

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.