P53 (15W6) Rabbit Monoclonal Antibody
Product Specifications
Background
Plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. It is postulated to bind as a tetramer to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor.
Product Name Alternative
Cellular tumor antigen p53; Phosphoprotein p53; TP53; Tumor suppressor p53
Swiss Prot
P04637
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, FC, IP
Field of Research
Cell Biology
Purification
Affinity purification
Dilution
WB 1:1000-1:5000, IHC 1:50-1:100, ICC/IF 1:100-1:200, FC 1:200-1:2000, IP 1:20-1:50
Form
Liquid
Buffer
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Modification
Unmodified
Molecular Weight
53kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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